The only FDA-approved medication that treats both erectile dysfunction and prostate symptoms with one daily pill.
Imagine not having to plan intimate moments around a pill. No clock-watching. No performance anxiety. Just confidence, every day.
That's the power of daily tadalafil (generic Cialis). Unlike medications you take "as needed," daily tadalafil keeps you ready 24/7—so you can be spontaneous when the moment feels right.
Even better? It's the only FDA-approved medication that treats both erectile dysfunction and prostate symptoms with one daily pill. Which means you might also sleep better at night—without waking up multiple times to use the bathroom.
Daily tadalafil (5mg) maintains steady levels in your system, so you don't need to time doses around activities.
First Few Days
Most men notice initial improvements
1-2 Weeks
Full benefits develop
24/7 Coverage
Ready whenever you are
Technical Note
Tadalafil is a PDE5 inhibitor FDA-approved for treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). Below, you'll find detailed clinical evidence supporting these uses.
Tadalafil is the only medication FDA-approved for both erectile dysfunction and benign prostatic hyperplasia at the 5mg daily dose.
In pivotal clinical studies, 84.5% of men taking tadalafil 5mg daily reported improved erections, with over half achieving normal erectile function.
In pooled analysis, 71.1% of men achieved clinically meaningful improvement in BPH symptoms, with 74.2% reporting feeling better overall.
The only medication for both
Simplify your treatment with one daily dose
Erectile dysfunction affects millions of men and can significantly impact quality of life, relationships, and self-confidence. Daily tadalafil (5mg) offers a proven approach with the convenience of consistent, around-the-clock support.
No need to plan around medication timing—be ready anytime
Steady medication in your system provides reliable support
Reduces performance anxiety by eliminating timing concerns
Partners report higher satisfaction with spontaneous intimacy
Clinical trials show sustained improvements over 2+ years of daily use
In the pivotal study that led to FDA approval, 84.5% of men taking tadalafil 5mg daily reported improved erections, compared to only 28.3% with placebo. Additionally, over half achieved normal erectile function—a more than 6-fold improvement over placebo. Long-term studies show these benefits are sustained, with 95.7% of men reporting improved erections after 2 years of daily use.
First Pivotal FDA Trial
Improved Erections
In this 12-week study of 268 men with ED, 84.5% of men taking tadalafil 5mg once daily reported improved erections, compared to only 28.3% taking placebo. Additionally, 51.5% of men achieved normal erectile function (no ED), versus just 8.3% with placebo—a more than 6-fold improvement.
2-Year Study of 5mg Daily
After 2 Years
In long-term extensions of the pivotal trials, 472 men continued taking tadalafil 5mg daily for up to 2 years. After 2 years of daily use, 95.7% of men reported improved erections. Erectile function improvements were maintained throughout the entire study period.
One of the most significant quality-of-life improvements from daily tadalafil (5mg) is the reduction in nocturia—waking up at night to urinate.
Disrupted sleep affects daytime energy and cognitive function
Multiple nighttime trips reduce overall sleep quality
Getting up in the dark increases fall risk, especially for older adults
Better sleep leads to improved overall health and wellbeing
Clinically Meaningful Improvement
In a pooled analysis of 1,499 patients, 71.1% of men taking tadalafil 5mg daily achieved clinically meaningful improvement in BPH symptoms (≥3-point reduction in IPSS), compared to only 56.0% with placebo. Separately, 74.2% reported feeling better overall.
71.1% of men taking tadalafil 5mg daily achieved clinically meaningful improvement in BPH symptoms (≥3-point improvement in IPSS), compared to only 56.0% with placebo. This large-scale analysis demonstrates consistent, patient-centered benefits.
Nickel JC, et al. BJU International. 2015;115(5):815-821.74.2% of patients taking tadalafil 5mg daily reported feeling better (Patient Global Impression of Improvement), compared to 57.6% with placebo. Improvements were visible after just 1 week of treatment.
Porst H, et al. European Urology. 2011;60(5):1105-1113.40.5% of men taking tadalafil 5mg daily were 'combined responders'—experiencing meaningful improvement in both ED and BPH—compared to only 18.3% with placebo. Men had 2.8× higher odds of combined response.
Roehrborn CG, et al. BJU International. 2016;118(1):153-162.Different types of research provide different levels of confidence in findings. Here's how to interpret the evidence behind daily tadalafil.
Erectile dysfunction and benign prostatic hyperplasia at 5mg daily dose
Supported by multiple large randomized controlled trials and regulatory review
Sleep quality improvements from reduced nighttime urination
Supported by multiple clinical studies in BPH populations
All clinical data presented on this page comes from peer-reviewed studies published in reputable medical journals. We encourage you to review the original research and discuss with your healthcare provider.
Tadalafil at a daily dose of 5mg is generally well-tolerated when used as prescribed. However, like all medications, it has potential side effects and important safety considerations.
For comprehensive safety information, contraindications, drug interactions, and detailed side effect information, please review our complete Tadalafil Safety Information page.
Most side effects are mild and decrease with continued use:
Never combine with nitrate medications
This combination can cause dangerous drops in blood pressure
Seek immediate medical attention
For erections lasting longer than 4 hours, sudden vision loss, or chest pain during activity
Daily low-dose tadalafil may be appropriate to discuss with a healthcare provider if you:
Have erectile dysfunction and prefer continuous support rather than timing doses
Experience BPH symptoms including nighttime urination affecting sleep quality
Have both ED and BPH symptoms (the only FDA-approved medication for both conditions)
Want consistent daily medication rather than as-needed dosing
Desire the spontaneity of not having to time medication around sexual activity
May be noticed within a few days, with optimal effects developing over 1-2 weeks
Typically noticeable within 4 weeks of daily use (primarily studied at 5mg dose)
Clinical trials demonstrate sustained effectiveness over 2+ years
Before Starting Any Medication
Individual results may vary — Response to medication differs between individuals
Clinical trial results do not guarantee individual outcomes — Your experience may differ
Always consult healthcare providers before starting any medication regimen
Never combine with other ED medications or certain recreational substances
Report any concerning symptoms to your healthcare provider promptly
These statements are based on clinical trials — Not all patients will experience the same results
Disclaimer: This information is for educational purposes only and should not replace professional medical advice. All clinical data presented is from published peer-reviewed studies. Individual results may vary and are not guaranteed. All treatment decisions should be made in consultation with a qualified healthcare provider who can evaluate your individual medical situation.
If you have questions about daily low-dose tadalafil, its benefits, safety profile, or whether it might be appropriate for your situation, please consult with one of our licensed healthcare providers during your consultation.
Disclaimer: This information is for educational purposes only and should not replace professional medical advice. All clinical data presented is from published peer-reviewed studies. Individual results may vary and are not guaranteed. All treatment decisions should be made in consultation with a qualified healthcare provider who can evaluate your individual medical situation.